Bicifadine hydrochloride

Catalog # Availability Size / Price Qty
4357/10
4357/50
Bicifadine hydrochloride | CAS No. 66504-75-4 | Adrenergic Transporter Inhibitors
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Description: Noradrenalin, 5-HT and dopamine re-uptake inhibitor

Chemical Name: 1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride

Purity: ≥98%

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Biological Activity

Potent antagonist of the noradrenalin transporter (IC50 = 55 nM); also displays antagonist activity at the 5-HT and dopamine transporters (IC50 values are 117 nM and 910 nM respectively). Orally active. Exhibits antinociceptive and antiallodynic activity in rodent models of acute, persistent, and chronic pain.

Technical Data

M.Wt:
209.72
Formula:
C12H15N.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
66504-75-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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