Biological ActivitySelective neuromedin B receptor (NMB-R, BB1) antagonist (Ki values are 216 and 18,264 nM for BB1 and BB2 receptors respectively). Displays no activity at a range of other receptors.
(Modifications: Disulfide bridge between 2 - 7, X-1 = D-Nal, Trp-4 = D-Trp, X-8 = Nal & C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery of a novel class of neuromedin B receptor antagonists, substituted somatostatin analogues.
Orbuch et al.
Pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin B receptors.
Ryan et al.
Role of different bombesin receptor subtypes mediating contractile activity in cat upper gastrointestinal tract.
Milusheva et al.
Citation for BIM 23042
The citations listed below are publications that use Tocris products. Selected citations for BIM 23042 include:
1 Citation: Showing 1 - 1
Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin
Authors: Blais Et al.
Neuroscience Letters 2016;633:262
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VersaClone cDNA Plasmids
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