BINA

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4048/10
4048/50
BINA | CAS No. 866823-73-6 | Group II mGluR Modulators
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Description: Selective positive allosteric modulator of mGlu2 receptors
Alternative Names: Biphenyl-indanone A

Chemical Name: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic acid

Purity: ≥98%

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Biological Activity

Selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). Displays no effect on glutamate-induced activation of other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.

Technical Data

M.Wt:
454.56
Formula:
C30H30O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
866823-73-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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