Chemical Name: N6-[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysine
Biological ActivityBiocytin is a versatile marker used in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays. Displays high solubility in aqueous solutions and has a low molecular weight facilitating injection using micropipettes. Can be incorporated with a variety of avidin and streptavidin conjugates for detection by light, fluorescence or electron microscope.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Current concepts in neuroanatomical tracing.
Kobbert et al.
Morphology and axonal projection pattern of neurons in the telencephalon of the fire-bellied toad Bombina orientalis: an anterograde, retrograde and intracellular biocytin labelling study.
Roth et al.
Biocytin wide-field bipolar cells in rabbit retina selectively contact blue cones.
MacNeil and Gaul
Citations for Biocytin
The citations listed below are publications that use Tocris products. Selected citations for Biocytin include:
12 Citations: Showing 1 - 10
Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization.
Authors: Roesler Et al.
Front Cell Neurosci 2019;13:330
Dendrite-Specific Amplification of Weak Synaptic Input during Network Activity In Vivo.
Authors: Ferrarese Et al.
Cell Rep 2018;24:3455
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.
Authors: Chai Et al.
Encoding of Discriminative Fear Memory by Input-Specific LTP in the Amygdala.
Authors: Kim and Cho
Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra.
Authors: Estakhr Et al.
Curr Biol 2017;27:1900
Identification and structure solution of fragment hits against kinetoplastid N-myristoyltransferase.
Authors: Robinson and Wyatt
Isolation, expansion and transplantation of postnatal murine progenitor cells of the enteric nervous system.
Authors: Dettmann Et al.
PLoS One 2014;9:e97792
Regulation of action potential waveforms by axonal GABAA receptors in cortical pyramidal neurons.
Authors: Xia Et al.
PLoS One 2014;9:e100968
hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice.
Authors: Cunningham Et al.
Cell Stem Cell 2014;15:559
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Authors: Tsai Et al.
Parallel optical control of spatiotemporal neuronal spike activity using high-speed digital light processing.
Authors: Jerome Et al.
Front Syst Neurosci 2011;5:70
Leptin does not directly affect CNS serotonin neurons to influence appetite.
Authors: Lam Et al.
Acta Crystallogr F Struct Biol Commun 2011;13:584
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