Muscarinic receptor antagonist that displays some selectivity for the M1
values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M1
receptors respectively). Alleviates extrapyramidal symptoms associated with antipsychotic drugs. Displays antiparkinsonian activity.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in chinese hamster ovary cells.
Bolden et al.
Muscarinic receptor occupancy by biperiden in living human brain.
Sudo et al.
Life Sci., 1999;64:PL99
Anticholinergic drugs used in Parkinson's disease: an overlooked class of drugs from a pharmacokinetic perspective.