2 results for "mAChR M1 Antagonists" in Products

mAChR M1 Antagonists

M1 receptors are members of the G-protein-coupled receptor (GPCR) family which are found mostly bound to Gq proteins. They are one of five muscarinic receptors that act to control the metabotropic functions of acetylcholine (ACh) in the central nervous system (CNS). M1 receptors are most densely populated in the neuronal cells of the cerebral cortex and hippocampus. Activation of the M1 receptor leads to several responses, including the upregulation of phospholipase C, the activation of ion ...

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Potent, selective M1 antagonist

Chemical Name: 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride
Purity: ≥98%
Potent, selective M1 antagonist
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Highly selective M1 antagonist

Chemical Name: N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Purity: ≥98%
Highly selective M1 antagonist
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