BL 1249

Catalog # Availability Size / Price Qty
3797/10
3797/50
BL 1249 | CAS No. 18200-13-0 | Two-P Potassium Channels Activators
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Description: K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

Chemical Name: 5,6,7,8-Tetrahydro-N-[2-(2H-tetrazol-5-yl)phenyl]-1-naphthalenamine

Purity: ≥99%

Product Details
Citations (1)
Reviews (1)

Biological Activity

K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel opener (EC50 values are 5.5 μM and 8 μM, respectively). Exhibits selectivity for bladder over vascular tissue in vitro and in vivo (EC50 values are 1.26 and 21.0 μM for cultured bladder and aortic tissues respectively).

Technical Data

M.Wt:
291.35
Formula:
C17H17N5
Solubility:
Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
18200-13-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for BL 1249

The citations listed below are publications that use Tocris products. Selected citations for BL 1249 include:

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BL 1249 performed ideally on biology lab conditions
By Anonymous on 10/31/2018
Species: Human

Great potassium channel activator. Was studied on potassium channel expressed on human brain cells. The product performed well under experimental conditions and would purchase again.


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