Catalog Number: 5488
Chemical Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Biological Activity
FPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.
Technical Data
  • M.Wt:
    192.21
  • Formula:
    C8H16O5
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Storage:
    Store at -20°C
  • CAS No:
    78606-80-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis.
    Chen et al.
    Mol.Cancer.Ther., 2010;9:2164
  2. BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats.
    Gong et al.
    Resuscitation., 2012;83:907
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