Potent cdk1/2 inhibitor (IC50
values are 6, 9 and 230 nM for cdk1, cdk2 and cdk4, respectively). Inhibits proliferation of HCT-116 colon cancer cells in vitro
External Portal InformationChemicalprobes.org
is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of BMS-265246
is reviewed on the chemical probes website.
Soluble to 50 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues.
Misra et al.