Chemical Name:(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl) (2,6-difluoro-4-methylphenyl)methanone
Biological Activity Potent cdk1/2 inhibitor (IC50 values are 6, 9 and 230 nM for cdk1, cdk2 and cdk4, respectively). Inhibits proliferation of HCT-116 colon cancer cells in vitro.
External Portal Information
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of BMS-265246 is reviewed on the chemical probes website.
Soluble to 50 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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