BMS 453

Catalog # Availability Size / Price Qty
3409/10
BMS 453 | CAS No. 166977-43-1 | Additional Retinoic Acid Receptor Compounds
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Description: Synthetic retinoid and RARβ agonist; also RARα and RARγ antagonist
Alternative Names: BMS 189453

Chemical Name: 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid

Product Details
Citations (3)
Reviews

Biological Activity

Synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.

Technical Data

Formula:
C27H24O2
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
166977-43-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for BMS 453

The citations listed below are publications that use Tocris products. Selected citations for BMS 453 include:

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