partial agonist and high affinity α1D
adrenoceptor antagonist (Ki
values are 2, 800 and 600 nM at cloned rat α1D
, rat α1A
and hamster α1B
receptors respectively). Also available as part of the α1-Adrenoceptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
The putative 5-HT1A receptor antagonists NAN-190 and BMY 7378 are partial agonists in the rat dorsal raphe nucleus in vitro.
Gruel and Glaser
The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle.
Piascik et al.
Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378.
Sharp et al.
Pharmacological evidence for β1D-adrenoceptors in the rabbit ventricular myocardium: analysis with BMY 7378.
Yang and Endoh
The citations listed below are publications that use Tocris products. Selected citations for BMY 7378 dihydrochloride include:
Showing Results 1 - 4 of 4