Chemical Name: N,N'-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide
Biological Activity Allosteric glutaminase (GLS1) inhibitor (IC50 = 3.3 μM). Selective for GLS1 over GLS2 and γ-glutamyl transpeptidase. Induces cell death of P493 human lymphoma B cells in vitro and reduces tumor volume of P493 cell xenografts in mice.
Soluble to 20 mM in DMSO
Store at -20°C
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