BQ 788 sodium salt

Tocris Bioscience | Catalog # 1500

Selective ETB antagonist
Tocris Bioscience

Key Product Details

Description

Selective ETB antagonist
View all Endothelin ETB Receptor Antagonists »

Product Description

BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells).

Product Specifications for BQ 788 sodium salt

Molecular Weight

663.79

Formula

C34H50N5NaO7

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine sodium salt

CAS Number

156161-89-6

PubChem ID

16759603

InChI Key

QCVIFBRTTLMEOV-FUKQNADPSA-M

SMILES

[Na+].CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C(=O)OC)C2=C1C=CC=C2)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 3.32 5

Preparing Stock Solutions for BQ 788 sodium salt

The following data is based on the product molecular weight 663.79.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 30.13 mL 150.65 mL 301.30 mL
0.25 mM 6.03 mL 30.13 mL 60.26 mL
0.5 mM 3.01 mL 15.07 mL 30.13 mL
2.5 mM 0.60 mL 3.01 mL 6.03 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 103 publications citing the usage of this product.

Product Documents for BQ 788 sodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BQ 788 sodium salt

For research use only

Citations for BQ 788 sodium salt

Customer Reviews for BQ 788 sodium salt (1)

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  • Product works great
    Name: Anonymous
    Assay Type: Ex Vivo
    Verified Customer | Posted 11/02/2017
    We utilized this product at 1uM to inhibit endothelin-B receptors ex vivo in mouse aortas followed by vasomotor function experiments. We have obtained superior results using this BQ788 product!
    BQ 788 sodium salt 1500

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