Chemical Name:N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride
Biological Activity Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice.
Soluble to 50 mM in water and to 50 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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