Human Breast Tissue Lysate (Adult Tumor)

Novus Biologicals | Catalog # NBP2-28016

Novus Biologicals
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Key Product Details

Species

Human

Product Summary for Human Breast Tissue Lysate (Adult Tumor)

The vial is provided with a 10% overfill. Maximum recovery can be obtained by centrifuging the vial briefly to collect any solution on the cap and tube sides.
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Product Specifications

Application Notes

These lysates are proteomic discovery tools.Researchers should validate and optimize for individual use. Potential applications MAY include WB, immunoprecipitation, protein-protein interactions, ligand binding, ELISA.
Note: For use in 1D and 2D gel electrophoresis, the addition of a denaturing gel loading buffer with reducing agents may be required.

Specificity

Sex:Female
Age :60
Grade:3
Stage:II
TNM:T2N1M0
Clinical Tissue
Human Breast Tumor Tissue Lysate, Soluble protein fraction

Type

Tissue

Life Stage

Adult

Tissue

Breast

Tissue Condition

Tumor

Scientific Data Images for Human Breast Tissue Lysate (Adult Tumor)

Human Breast Tissue Lysate (Adult Tumor) [NBP2-28016]
Human Breast Tissue Lysate (Adult Tumor) [NBP2-28016]

Formulation, Preparation, and Storage

Preparation Method

Tissue specimens are homogenized in modified RIPA buffer to obtain the soluble proteins, and centrifuged to clarify. The pellet was further extracted with a second buffer to obtain the less soluble protein fraction. The lysate solution may appear turbid at cold temperatures due to insolubility of buffer components. The solution should clear upon warming to room temperature.

Concentration

1 mg/ml

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20C short term. Aliquot and store at -70C long term. Avoid freeze-thaw cycles.

Product Documents for Human Breast Tissue Lysate (Adult Tumor)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Human Breast Tissue Lysate (Adult Tumor)

The vial is provided with a 10% overfill. Maximum recovery can be obtained by centrifuging the vial briefly to collect any solution on the cap and tube sides.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Protocols

View specific protocols for Human Breast Tissue Lysate (Adult Tumor) (NBP2-28016):

Product Handling Protocol (NBP2-28016):
Lysate Preparation: Tissue specimens are homogenized in modified RIPA buffer to obtain the soluble proteins, and
centrifuged to clarify. The pellet was further extracted with a second buffer to obtain the less
soluble protein fraction. The lysate solution may appear turbid at cold temperatures due to
insolubility of buffer components. The solution should clear upon warming to room temperature.
Extraction 1: PBS, pH 7.4 1 ug/ml Aprotinin 1 mM NaF
Modified RIPA Buffer: 1 mM EDTA 1 ug/ml Pepstatin-A 0.1% SDS
0.25% Na deoxycholate 1 ug/ml Leupeptin 1 mM PMSF
1 mM Na3VO4
Extraction 2: PBS, pH 7.4, 5.0 M Urea, 2.0 M Thiourea, 50mM DTT, 0.1% SDS

FAQs

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