BRL 37344, sodium salt

  ( 9 citations )    
Product Datasheet
Catalog Number:0948
Chemical Name:(R*,R*)-(±)-4-[2-[(2-(3-Chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxyacetic acid, sodium salt
Product Details
Citations (9)
Supplemental Products
Reviews
Biological Activity
Potent and selective β3 adrenoceptor agonist (Ki values are 287, 1750 and 1120 nM for β3, β1 and β2 receptors respectively). Also available as part of the β-Adrenoceptor Agonist Tocriset™.
Technical Data
  • M.Wt:
    385.82
  • Formula:
    C19H21NO4ClNa
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    127299-93-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of GlaxoSmithKline
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BRL 37344, sodium salt include:

9 Citations: Showing 1 - 9
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  1. β2-Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression.
    Authors: Lavine
    Invest Ophthalmol Vis Sci  2017;58(1):299
  2. Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands.
    Authors: Littmann Et al.
    Dev Neurosci  2015;355:183
  3. Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat.
    Authors: Suárez Et al.
    Dis Model Mech  2014;7:129
  4. Attenuation of choroidal neovascularization by β(2)-adrenoreceptor antagonism.
    Authors: Lavine Et al.
    JAMA Ophthalmol  2013;131:376
  5. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.
    Authors: Rankovic Et al.
    PLoS One  2011;6:e27474
  6. Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors.
    Authors: Maupoil Et al.
    Br J Pharmacol  2007;150:899
  7. ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.
    Authors: Brahmadevara Et al.
    Br J Pharmacol  2004;142:781
  8. β 3-adrenergic receptors regulate retinal endothelial cell migration and proliferation.
    Authors: Steinle Et al.
    J Pharmacol Exp Ther  2003;278:20681
  9. Involvement of β 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function.
    Authors: Cirino Et al.
    J Biol Chem  2003;100:5531

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