BRL 37344, sodium salt

Key Product Details

Product Description

BRL 37344, sodium salt is a potent and selective β₃ adrenoceptor agonist (K_i values are 287, 1750 and 1120 nM for β₃, β₁ and β₂ receptors respectively).

Licensing Information

Sold with the permission of GlaxoSmithKline

Product Specifications for BRL 37344, sodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BRL 37344, sodium salt

The following data is based on the product molecular weight 385.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.59 mL	12.96 mL	25.92 mL
5 mM	0.52 mL	2.59 mL	5.18 mL
10 mM	0.26 mL	1.30 mL	2.59 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Strosberg and Pietri-Rouxel Function and regulation of the β₃-adrenoceptor. TiPS 1996 PMID: 8979772
• Ayo Oriowo The selectivity in vitro of the sterioisomers of the beta-3 adrenoreceptor agonist BRL 37344. J.Pharmacol.Exp.Ther. 1996 PMID: 8613923
• Board BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro. Eur.J.Pharmacol. 2000 PMID: 11011029
• Arch Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature 1984 PMID: 6325935

Product Documents for BRL 37344, sodium salt