Bryostatin 1

Catalog # Availability Size / Price Qty
2383/10U

Save Up to 40% on RUO Reagents with BIOSPRING24 (See Details)

Bryostatin 1 | CAS No. 83314-01-6 | Protein Kinase C Activators
1 Image
Description: Protein kinase C activator
Alternative Names: NSC 339555

Chemical Name: (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl-(2E, 4E)-2,4-octadienoic acid ester

Purity: ≥98%

Product Details
Citations (6)
Reviews

Biological Activity

Bryostatin 1 is a protein kinase C (PKC) activator that binds with high affinity (Ki = 1.35 nM). Initially activates and subsequently induces downregulation of PKC isozymes. Sensitizes tumor cells to cytotoxic effects of anticancer agents. Restores hippocampal synapses and spatial learning and memory in an in vivo model of fragile X syndrome.

Technical Data

M.Wt:
905.04
Formula:
C47H68O17
Solubility:
Soluble in DMSO and in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
83314-01-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Bryostatin 1

The citations listed below are publications that use Tocris products. Selected citations for Bryostatin 1 include:

6 Citations: Showing 1 - 6

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Bryostatin 1

There are currently no reviews for this product. Be the first to review Bryostatin 1 and earn rewards!

Have you used Bryostatin 1?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.