Bryostatin 3

Tocris Bioscience | Catalog # 5238

Potent protein kinase C activator
Tocris Bioscience
Discontinued Product
5238 has been discontinued. View all Protein Kinase C Activators products.

Key Product Details

Description

Potent protein kinase C activator
View all Protein Kinase C Activators »

Product Description

Bryostatin 3 is a potent protein kinase C activator (KI = 2.75 nM). Attenuates phorbol 12-myristate 13-acetate (Cat. No. 1201) inhibition of GH4C1 pituitary cell proliferation in vitro.

Product Specifications for Bryostatin 3

Molecular Weight

888.99

Formula

C46H64O17

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(4S,5S,7E,9R,11Z,13S,15S,17S,19R,21R,25R,27R,27aS)-17-(Acetyloxy)-4,5,6,9,10,11,12,13,14,15,16,17,18,19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester

CAS Number

143370-84-7

PubChem ID

10395929

InChI Key

BSNHYLUEHJOXFN-HBUIWOJHSA-N

SMILES

O=C(O[C@@H]([C@@H](C)O)C[C@@H](O5)[C@H]3O4)C[C@H](O)C[C@H](C[C@H](OC(C)=O)C(C)2C)O[C@@]2(O)C[C@H](C1)O[C@@H](/C=C/C(C)(C)[C@@]5(O)[C@@H](OC(/C=C/C=C/CCC)=O)C3=CC4=O)C/C1=C\C(OC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Bryostatin 3

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bryostatin 3

For research use only

Related Research Areas

Diabetes
Intracellular Kinases

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