Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50
~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
A small-molecule inhibitor of skeletal muscle myosin II.
Cheung et al.
Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide.
Shaw et al.
Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis.
Ramachandran et al.
Cell Motil.Cytoskeleton, 2003;55:61
The citations listed below are publications that use Tocris products. Selected citations for BTS include:
Showing Results 1 - 4 of 4