BTT 3033

  ( 1 citations )    
Product Datasheet
Catalog Number:4724
Chemical Name:1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide
Product Details
Citations (1)
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Biological Activity
Selective inhibitor of integrin α2β1 (EC50 = 130 nM for α2β1 binding to collagen I). Binds to the α2I domain. Exhibits selectivity for α2β1 over integrins α3β1, α4β1, α5β1 and αv. Inhibits platelet aggregation to collagen I coated capillaries under flow. Also inhibits binding of α2-expressing CHO cells to collagen I under shear stress conditions.
Technical Data
  • M.Wt:
    465.5
  • Formula:
    C23H20FN5O3S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    1259028-99-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for BTT 3033 include:

1 Citations: Showing 1 - 1

  1. Collagen Type 1 accelerates healing of ruptured fetal membranes.
    Authors: Mogami
    Sci Rep  2018;8(1):696

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