BU 224 hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:0725
Chemical Name:2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
High affinity ligand for the imidazoline I2 binding site (Ki = 2.1 nM). Putative I2 antagonist; antagonizes the effects of imidazoline ligands on morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.
Technical Data
  • M.Wt:
    233.7
  • Formula:
    C12H11N3.HCl
  • Solubility:
    Soluble to 10 mM in DMSO
  • Storage:
    Desiccate at RT
  • CAS No:
    205437-64-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BU 224 hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
    Authors: Gründemann Et al.
    Br J Pharmacol  2002;137:910
  2. Activation of I(2)-imidazoline receptors enhances supraspinal morphine analgesia in mice: a model to detect agonist and antagonist activities at these receptors.
    Authors: Sánchez-Blázquez Et al.
    Br J Pharmacol  2000;130:146

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