partial agonist with relatively high affinity (Ki
= 9.3 - 29.5 nM). A clinically effective anxiolytic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
Comparative behavioural profiles of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine (1-PP) in the murine elevated plus-maze.
Cao and Rodgers
Buspirone - a preliminary review on its pharmacological properties and therapeutic efficacy as an anxiolytic.
Goa and Ward
Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of α2-adrenoceptors unde
Gobert et al.
The citations listed below are publications that use Tocris products. Selected citations for Buspirone hydrochloride include:
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