Butabindide oxalate

Key Product Details

Product Description

Butabindide oxalate is a high affinity, reversible, selective and competitive inhibitor of a CCK-inactivating serine protease (tripeptidyl peptidase II) (K_i = 7 nM). Active in vivo (ID₅₀ = 1.1 and 6.8 mg/kg i.v. for inhibition of liver and brain enzyme respectively).

Licensing Information

Sold with the permission of INSERM and UCL

Product Specifications for Butabindide oxalate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Butabindide oxalate

The following data is based on the product molecular weight 393.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.54 mL	12.71 mL	25.42 mL
5 mM	0.51 mL	2.54 mL	5.08 mL
10 mM	0.25 mL	1.27 mL	2.54 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Renn Characterization and cloning of tripeptidyl peptidase II from the fruit fly, Drosophila melanogaster. J.Biol.Chem. 1998 PMID: 9668104
• Rose Characterization and inhibition of a cholecystokinin-inactivating serine peptidase. Nature 1996 PMID: 8602240
• Ganellin Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J.Med.Chem. 2000 PMID: 10691692

Product Documents for Butabindide oxalate