BVT 948

Catalog # Availability Size / Price Qty
2176/10
2176/50
BVT 948 | CAS No. 39674-97-0 | Protein Tyrosine Phosphatase Inhibitors
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Description: Non-competitive protein tyrosine phosphatase inhibitor

Chemical Name: 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

Non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Also inhibits several cytochrome P450 isoforms (IC50 <10 μM).

Technical Data

M.Wt:
241.25
Formula:
C14H11NO3
Solubility:
Soluble to 50 mM in ethanol and to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
39674-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for BVT 948

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2 Citations: Showing 1 - 2

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