C-DIM 12

   
Product Datasheet
Catalog Number:5821
Chemical Name:3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole]
Product Details
Reviews
Biological Activity
Nurr1 activator. Inhibits NF-κB and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. Neuroprotective in a mouse Parkinson's disease model. Orally bioavailable.
Technical Data
  • M.Wt:
    356.85
  • Formula:
    C23H17ClN2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    178946-89-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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