Biological Activity Nurr1 activator. Inhibits NF-κB and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. Neuroprotective in a mouse Parkinson's disease model. Orally bioavailable.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at -20°C
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