c-JUN peptide (CAS 610273-01-3): R&D Systems
Catalog Number: 1989
Biological Activity
Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
Technical Data
  • M.Wt:
    2743.55
  • Formula:
    C121H210N36O34S
  • Sequence:
    ILKQSMTLNLADPVGSLKPHLRAKN
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    610273-01-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN d domain induces apoptosis and affects a distinct set of interleukin-1 induced inflammatory genes.
    Holzberg et al.
    J.Biol.Chem., 2003;278:40213
Citations:

The citations listed below are publications that use Tocris products. Selected citations for c-JUN peptide include:

1 Citations: Showing 1 - 1

  1. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.
    Authors: Moreau Et al.
    J Urol 2015;6:8045

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