Biological Activityc-JUN peptide is a peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
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Citations for c-JUN peptide
The citations listed below are publications that use Tocris products. Selected citations for c-JUN peptide include:
2 Citations: Showing 1 - 2
Inhibiting IL-1 signaling pathways to inhibit catabolic processes in disc degeneration.
Authors: Daniels Et al.
J Orthop Res 2017;35:74
Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.
Authors: Moreau Et al.
J Urol 2015;6:8045
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