C-type natriuretic peptide (1-22) (human, rat, swine)

Tocris Bioscience | Catalog # 3520

Endogenous peptide agonist at NPR2
Tocris Bioscience

Key Product Details

Description

Endogenous peptide agonist at NPR2
View all Natriuretic Peptide Receptor Agonists »

Product Description

C-type natriuretic peptide (1-22) (human, rat, swine) is an endogenous peptide found in plasma and cerebrospinal fluid. Behaves as an agonist at natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). Inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo.

Product Specifications for C-type natriuretic peptide (1-22) (human, rat, swine)

Molecular Weight

2197.61

Formula

C93H157N27O28S3

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

127869-51-6

PubChem ID

16179407

InChI Key

UHSBKBYWHCBDCJ-DYGWFTAGSA-N

SMILES

[H]NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for C-type natriuretic peptide (1-22) (human, rat, swine)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for C-type natriuretic peptide (1-22) (human, rat, swine)

For research use only

Citations for C-type natriuretic peptide (1-22) (human, rat, swine)

Customer Reviews for C-type natriuretic peptide (1-22) (human, rat, swine) (1)

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  • NP in vitro
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 08/05/2018
    Used in vitro to investigate different roles of NP family members.

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