C34

Catalog # Availability Size / Price Qty
5373/10
5373/50
C34 | CAS No. 40592-88-9 | Toll-like Receptor Inhibitors
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Description: TLR4 inhibitor
Alternative Names: TLR4-IN-C34

Chemical Name: 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate

Product Details
Citations (4)
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Biological Activity

TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo. Displays no significant effects on signaling via TLR2 or TLR9.

Technical Data

M.Wt:
389.4
Formula:
C17H27NO9
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Storage:
Store at -20°C
CAS No:
40592-88-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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