Catalog Number: 3193
Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate
Biological Activity
Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.
Technical Data
  • M.Wt:
    494.52
  • Formula:
    C20H22N4O5.CH3SO3H
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    59721-29-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas.
    Horiuchi et al.
    J.Pharmacol.Exp.Ther., 1990;252:320
  2. The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
    Ishikura et al.
    Life Sci., 2007;80:1999
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Camostat mesylate include:

3 Citations: Showing 1 - 3
Filter your results:

  1. Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.
    Authors: Shirato Et al.
    J Virol 2013;87:12552
  2. Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice.
    Authors: Gamble Et al.
    Leukemia 2013;185:41518
  3. Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.
    Authors: Kawase Et al.
    J Virol 2012;86:6537

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