Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.
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Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas.
Horiuchi et al.
The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
Ishikura et al.
Life Sci., 2007;80:1999
The citations listed below are publications that use Tocris products. Selected citations for Camostat mesylate include:
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