Prodrug of the angiotensin II receptor 1 (AT1
) antagonist candesartan
(Cat. No. 4791), which exhibits antihypertensive effects in animal models.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Candesartan cilexetil: a review of its preclinical pharmacology.
Nishikawa et al.
Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (±)-1-(cyclohexyloxycarbonylo
Shibouta et al.