Candesartan cilexetil (CAS 145040-37-5): R&D Systems
Catalog Number: 4792
Alternate Names: TCV 116
Chemical Name: 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester
Biological Activity
Prodrug of the angiotensin II receptor 1 (AT1) antagonist candesartan (Cat. No. 4791), which exhibits antihypertensive effects in animal models.
Technical Data
  • M.Wt:
    610.66
  • Formula:
    C33H34N6O6
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    145040-37-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Candesartan cilexetil: a review of its preclinical pharmacology.
    Nishikawa et al.
    J.Hum.Hypertens., 1997;Suppl2:9
  2. Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (±)-1-(cyclohexyloxycarbonylo
    Shibouta et al.
    J.Pharmacol.Exp.Ther., 1993;266:114
Tocris Small Molecules
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Candesartan

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