Chemical Name: 2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol
Biological ActivityPartial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membranes).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cannabigerol behaves as a partial agonist at both CB1 and CB2 receptors.
Gauson et al.
Symposium on the Cannabinoids, 2007;:206
Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist.
Cascio et al.
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.
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