Carbamoylcholine chloride

Catalog # Availability Size / Price Qty
2810/100
Carbamoylcholine chloride | CAS No. 51-83-2 | Additional Nicotinic Receptor Agonists
1 Image
Description: Non-selective cholinergic agonist
Alternative Names: Carbachol

Chemical Name: (2-Hydroxyethyl)trimethylammonium chloride carbamate

Product Details
Citations (11)
Reviews (1)

Biological Activity

Cholinergic receptor agonist that is resistant to the action of cholinesterases. Blocks apoptosis in cerebellar granule neurons.

Technical Data

M.Wt:
182.65
Formula:
C6H15ClN2O2
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Storage:
Desiccate at RT
CAS No:
51-83-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Carbamoylcholine chloride

The citations listed below are publications that use Tocris products. Selected citations for Carbamoylcholine chloride include:

11 Citations: Showing 1 - 10

  1. Optically Induced Calcium-Dependent Gene Activation and Labeling of Active Neurons Using CaMPARI and Cal-Light.
    Authors: Ebner Et al.
    Front Synaptic Neurosci  2019;11:16
  2. DA D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson�s disease.
    Authors: Tozzi
    Cell Death Dis  2018;9(2):204
  3. The brain is required for normal muscle and nerve patterning during early Xenopus development.
    Authors: Herrera-Rincon Et al.
    Nat Commun  2017;8:587
  4. Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons.
    Authors: Athilingam Et al.
    Elife  2017;6
  5. Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor.
    Authors: Jovancevic Et al.
    Basic Res Cardiol  2017;112:13
  6. Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex.
    Authors: Martin Et al.
    Stem Cell Reports  2015;9:457
  7. Motilin Stimulates Gastric Acid Secretion in Coordination with Ghrelin in Suncus murinus.
    Authors: Goswami Et al.
    PLoS One  2015;10:e0131554
  8. Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
    Authors: Svalø Et al.
    Front Cell Neurosci  2015;10:e0117350
  9. Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.
    Authors: Deng Et al.
    J Pharmacol Toxicol Methods  2013;68:323
  10. G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.
    Authors: Hwangpo Et al.
    J Biol Chem  2012;287:13674

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Carbamoylcholine chloride

Average Rating: 4 (Based on 1 Review)

5 Star
0%
4 Star
100%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Carbamoylcholine chloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Carbachol releases Ca2+ from ER stores in HEK293 cells.
By Anonymous on 12/15/2018
Application: Species: Human

HEK293 cells were loaded with 1 µM cytosolic Ca2+ sensitive dye, Fura-2AM in normal tyrode solution for 30 min and excited alternately at 340 and 380 nm and fluorescence was captured at 510 nm. ER Ca2+ store was depleted with 100 µM carbachol (CCh) in nominally Ca2+ free tyrode solution, resulting in transient cytosolic Ca2+ peak.


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.