Chemical Name: (2-Hydroxyethyl)trimethylammonium chloride carbamate
Biological ActivityCholinergic receptor agonist that is resistant to the action of cholinesterases. Blocks apoptosis in cerebellar granule neurons.
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Activation of muscarinic cholinergic receptors blocks apoptosis of cultured cerebellar granule neurons.
Yan et al.
Citations for Carbamoylcholine chloride
The citations listed below are publications that use Tocris products. Selected citations for Carbamoylcholine chloride include:
11 Citations: Showing 1 - 10
Optically Induced Calcium-Dependent Gene Activation and Labeling of Active Neurons Using CaMPARI and Cal-Light.
Authors: Ebner Et al.
Front Synaptic Neurosci 2019;11:16
DA D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson�s disease.
Cell Death Dis 2018;9(2):204
The brain is required for normal muscle and nerve patterning during early Xenopus development.
Authors: Herrera-Rincon Et al.
Nat Commun 2017;8:587
Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons.
Authors: Athilingam Et al.
Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor.
Authors: Jovancevic Et al.
Basic Res Cardiol 2017;112:13
Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex.
Authors: Martin Et al.
Stem Cell Reports 2015;9:457
Motilin Stimulates Gastric Acid Secretion in Coordination with Ghrelin in Suncus murinus.
Authors: Goswami Et al.
PLoS One 2015;10:e0131554
Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
Authors: Svalø Et al.
Front Cell Neurosci 2015;10:e0117350
Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.
Authors: Deng Et al.
J Pharmacol Toxicol Methods 2013;68:323
G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.
Authors: Hwangpo Et al.
J Biol Chem 2012;287:13674
Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitro.
Authors: Silva Et al.
Br J Pharmacol 2007;151:195
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HEK293 cells were loaded with 1 µM cytosolic Ca2+ sensitive dye, Fura-2AM in normal tyrode solution for 30 min and excited alternately at 340 and 380 nm and fluorescence was captured at 510 nm. ER Ca2+ store was depleted with 100 µM carbachol (CCh) in nominally Ca2+ free tyrode solution, resulting in transient cytosolic Ca2+ peak.