Carbenoxolone disodium

Tocris Bioscience | Catalog # 3096

Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
Tocris Bioscience

Key Product Details

Description

Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
View all Gap Channel Blockers »

Product Description

Carbenoxolone disodium is a glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.

Product Specifications for Carbenoxolone disodium

Molecular Weight

614.72

Formula

C34H48Na2O7

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium

CAS Number

7421-40-1

PubChem ID

636402

InChI Key

BQENDLAVTKRQMS-SBBGFIFASA-L

SMILES

[Na+].[Na+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CCC([O-])=O)C(C)(C)[C@]3([H])CC[C@@]12C)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 61.47 100

Preparing Stock Solutions for Carbenoxolone disodium

The following data is based on the product molecular weight 614.72.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.63 mL 8.13 mL 16.27 mL
5 mM 0.33 mL 1.63 mL 3.25 mL
10 mM 0.16 mL 0.81 mL 1.63 mL
50 mM 0.03 mL 0.16 mL 0.33 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 35 publications citing the usage of this product.

Product Documents for Carbenoxolone disodium

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Carbenoxolone disodium

For research use only

Related Research Areas

Ion Channels and Regulators

Citations for Carbenoxolone disodium

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