Catalog Number: 3096
Chemical Name: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium
Biological Activity
Glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Differential inhibition of 11 beta-hydroxysteroid dehydrogenase by carbenoxolone in rat brain regions and peripheral tissues.
    Jellinck et al.
    J.Steroid Biochem.Mol.Biol., 1993;46:209
  2. Carbenoxolone inhibits junctional trasnfer and upregulates connexin43 expression by a protein kinase A-dependent pathway.
    Sagar and Larson
    J.Cell.Biochem., 2006;98:1543

The citations listed below are publications that use Tocris products. Selected citations for Carbenoxolone disodium include:

Showing Results 1 - 1 of 1

  1. Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles.
    Authors: Shuhaibar Et al.
    Proc Natl Acad Sci U S A
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