CBM 301940

Catalog # Availability Size / Price Qty
6319/10
Decarboxylase Inhibitors Small Molecule
1 Image
Description: Potent malonyl-CoA decarboxylase inhibitor; orally bioavailable

Chemical Name: tert-Butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent malonyl-CoA decarboxylase (MCD) inhibitor (IC50 = 23 nM). Suppresses malonyl-CoA degradation and fatty acid oxidation in isolated rat hearts, leading to secondary increase in glucose oxidation. Improves cardiac function during reperfusion of ischemic isolated rat hearts. Orally bioavailable.

Technical Data

M.Wt:
422.32
Formula:
C15H20F6N2O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
902146-11-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CBM 301940

There are currently no reviews for this product. Be the first to review CBM 301940 and earn rewards!

Have you used CBM 301940?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.