Catalog Number: 0452
Chemical Name: Carbonyl cyanide 3-chlorophenylhydrazone
Biological Activity
Widely used uncoupler of oxidative phosphorylation.
Technical Data
  • M.Wt:
    204.62
  • Formula:
    C9H5ClN4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    555-60-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A new class of uncoupling agents - carbonyl cyanide phenylhydrazones.
    Heytler and Pritchard
    Biochem.Biophys.Res.Commun., 1962;7:272
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CCCP include:

3 Citations: Showing 1 - 3
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  1. Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.
    Authors: Guo Et al.
    Curr Protoc Chem Biol 2015;7:141
  2. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria.
    Authors: Choubey Et al.
    Autophagy 2014;10:1105
  3. Presynaptic mitochondria in functionally different motor neurons exhibit similar affinities for Ca2+ but exert little influence as Ca2+ buffers at nerve firing rates in situ.
    Authors: Chouhan Et al.
    J Neurosci 2010;30:1869

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