Chemical Name: Carbonyl cyanide 3-chlorophenylhydrazone
Biological ActivityWidely used uncoupler of oxidative phosphorylation.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A new class of uncoupling agents - carbonyl cyanide phenylhydrazones.
Heytler and Pritchard
Citations for CCCP
The citations listed below are publications that use Tocris products. Selected citations for CCCP include:
4 Citations: Showing 1 - 4
Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.
Authors: Guo Et al.
Curr Protoc Chem Biol 2015;7:141
Efavirenz induces neuronal autophagy and mitochondrial alterations.
J Pharmacol Exp Ther 2014;351:250
BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria.
Authors: Choubey Et al.
Presynaptic mitochondria in functionally different motor neurons exhibit similar affinities for Ca2+ but exert little influence as Ca2+ buffers at nerve firing rates in situ.
Authors: Chouhan Et al.
J Neurosci 2010;30:1869
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TMRM fluorescence intensity before and after CCCP addition was used for the quantitation of change in mitochondrial membrane potential in spinal cord neurons induced by glutamate receptor agonist AMPA