Recombinant Mouse CCL2/MCP1 His Protein

Novus Biologicals | Catalog # NBP2-22772

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

Functional Assay, SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 24-148 of Mouse His-tag CCL2/MCP1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQPDAVNAPL TCCYSFTSKM IPMSRLESYK RITSSRCPKE AVVFVTKLKR EVCADPKKEW VQTYIKNLDR NQMRSEPTTL FKTASALRSS APLNVKLTRK SEANASTTFS TTTSSTSVGV TSVTVN

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Use in In vivo reported in scientific literature (PMID:33510218)

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse CCL2/MCP1 His Protein

SDS-PAGE: Recombinant Mouse CCL2/MCP1 His Protein [NBP2-22772]

SDS-PAGE: Recombinant Mouse CCL2/MCP1 His Protein [NBP2-22772]

SDS-Page: Recombinant Mouse CCL2/MCP1 Protein [NBP2-22772]

Formulation, Preparation, and Storage

NBP2-22772
Formulation PBS (pH 7.4), 10% glycerol
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCL2/MCP1

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant mouse CCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

C-C motif chemokine 2, chemokine (C-C motif) ligand 2, GDCF-2, HC11Monocyte secretory protein JE, MCAFMonocyte chemotactic and activating factor, MCP1 Monocyte chemotactic protein 1, MCP-1 Small-inducible cytokine A2, MGC9434, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, SCYA2HSMCR30, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF

Gene Symbol

CCL2

Additional CCL2/MCP1 Products

Product Documents for Recombinant Mouse CCL2/MCP1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Mouse CCL2/MCP1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations for Recombinant Mouse CCL2/MCP1 His Protein

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