CCT 137690

Catalog # Availability Size / Price Qty
4291/10
4291/50
CCT 137690 | CAS No. 1095382-05-0 | Aurora Kinase Inhibitors
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Description: Potent pan-Aurora kinase inhibitor

Chemical Name: 6-Bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-3H-imidazo[4,5-b]pyridine

Purity: ≥98%

Product Details
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Biological Activity

Potent inhibitor of Aurora kinases (IC50 values are 0.015, 0.019 and 0.025 μM at Aurora A, Aurora C and Aurora B respectively). Displays antiproliferative activity in a range of human tumor cell lines. Orally bioavailable.

Technical Data

M.Wt:
551.48
Formula:
C26H31BrN8O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1095382-05-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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