CD 2665

Key Product Details

Product Description

CD 2665 is a selective RARβγ antagonist (K_D values are 110, 306 and > 1000 nM for RARγ, RARβ and RARα respectively). Blocks retinoic acid-induced apoptosis ex vivo.

Product Specifications for CD 2665

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CD 2665

The following data is based on the product molecular weight 486.60.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.06 mL	10.28 mL	20.55 mL
5 mM	0.41 mL	2.06 mL	4.11 mL
10 mM	0.21 mL	1.03 mL	2.06 mL
50 mM	0.04 mL	0.21 mL	0.41 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 34 publications citing the usage of this product.

• Meister Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma selectivity binding retinoids in neuroblastoma. Anticancer Res. 1998 PMID: 9673404
• Kim The role of specific retinoid receptors in sebocyte growth and differentiation in culture. J.Invest.Dermatol. 2000 PMID: 10651997
• Szondy Induction of apoptosis by retinoids and retinoic acid receptor γ-selective compounds in mouse thymocytes through a novel apoptosis pathway. Mol.Pharmacol. 1997 PMID: 9187263

Product Documents for CD 2665