hh CD 3254 (CAS 196961-43-0): R&D Systems
Catalog Number: 3302
Chemical Name: 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Biological Activity
Selective RXRα agonist; exhibits no activity at RARα, RARβ or RARγ receptors.
Technical Data
  • M.Wt:
    364.48
  • Formula:
    C24H28O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >97%
  • Storage:
    Store at -20°C
  • CAS No:
    196961-43-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.
    Pogenberg et al.
    J.Biol.Chem., 2005;280:1625
  2. Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors.
    le Maire et al.
    EMBO.Rep., 2009;10:367
  3. Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function.
    Nahoum et al.
    Proc.Natl.Acad.Sci., 2007;104:17323

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