Chemical Name: 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Biological ActivitySelective RXRα agonist; exhibits no activity at RARα, RARβ or RARγ receptors.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors.
Le Maire et al.
EMBO Rep., 2009;10:367
Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.
Pogenberg et al.
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function.
Nahoum et al.
Citation for CD 3254
The citations listed below are publications that use Tocris products. Selected citations for CD 3254 include:
1 Citation: Showing 1 - 1
Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation.
Authors: Wang Et al.
J Mol Cell Biol 2017;9:338
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