CD22L-N3 (BPC-Sia-LacNAc-N3)

Tocris Bioscience | Catalog # 8830

CD22 ligand with azide group for onward chemistry
Tocris Bioscience

Key Product Details

Description

CD22 ligand with azide group for onward chemistry
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Product Description

CD22L-N3 (BPC-Sia-LacNAc-N3) is a functionalized CD22 receptor ligand for trogocytosis targeting chimera (TrogoTAC) research and development. CD22 targeted TrogoTACs are bispecific molecules capable of inducing protein transfer from the target cell to B cells, by redirecting trogocytosis. Comprises an azide functionalized CD22 ligand for conjugation.

Product Specifications for CD22L-N3 (BPC-Sia-LacNAc-N3)

Molecular Weight

922.89

Formula

C40H54N6O19

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(2R,4S,5R,6R)-6-((1R,2R)-3-([1,1'-Biphenyl]-4-carboxamido)-1,2-dihydroxypropyl)-5-acetamido-2-(((2R,3R,4S,5R,6S)-6-(((2R,3S,4R,5R,6R)-5-acetamido-6-(2-azidoethoxy)-4-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-4-hydroxytetrahydro-2H-pyran-2-carboxylic acid

CAS Number

1019642-47-7

PubChem ID

101550018

InChI Key

UTCPJMHBEGWJPH-LPKWDFCZSA-N

SMILES

O(C[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](OCCN=[N+]=[N-])[C@H](NC(C)=O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O)[C@@]3(C(O)=O)O[C@@]([C@@H]([C@@H](CNC(=O)C4=CC=C(C=C4)C5=CC=CC=C5)O)O)([C@H](NC(C)=O)[C@@H](O)C3)[H]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 92.29 100
DMSO 92.29 100

Preparing Stock Solutions for CD22L-N3 (BPC-Sia-LacNAc-N3)

The following data is based on the product molecular weight 922.89.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.08 mL 5.42 mL 10.84 mL
5 mM 0.22 mL 1.08 mL 2.17 mL
10 mM 0.11 mL 0.54 mL 1.08 mL
50 mM 0.02 mL 0.11 mL 0.22 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Till Trogocytosis targeting chimeras (TrogoTACs) for targeted protein transfer. ChemRxiv

Product Documents for CD22L-N3 (BPC-Sia-LacNAc-N3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD22L-N3 (BPC-Sia-LacNAc-N3)

For research use only

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