CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-12067

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # BAG 75E5

Format

Azide and BSA Free
View all CD41/CD61 Primary Antibodies »

Product Specifications

Immunogen

This antibody was raised by immunising mice with human CD41/CD61.

Specificity

This antibody recognises CD41/CD61 antigen.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Scientific Data Images for CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free [NBP3-12067]

Immunocytochemistry/ Immunofluorescence: CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free [NBP3-12067]

Immunocytochemistry/Immunofluorescence: CD41/CD61 Antibody (BAG 75E5) - Chimeric [NBP3-12067] - Immunofluorescence analysis of paraformaldehyde fixed human peripheral blood leukocytes on Shi-fix(TM) coverslips stained with the chimeric rabbit IgG version BAG 75E5 (NBP3-12067) at 10 ug/ml for 1h followed by Alexa Fluor(R) 488 secondary antibody (2 ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom NBP3-12067, DAPI, merged channels and an isotype control. The isotype control was an unknown specificity antibody followed by staining with Alexa Fluor(R) 488 secondary antibody.

Applications for CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: CD41/CD61

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Alternate Names

CD41, CD41 antigen, CD41BHPA3, GP2Bintegrin alpha-IIb, GPalpha IIb, GPIIb, GTA, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41), integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B), ITGAB, platelet fibrinogen receptor, alpha subunit, Platelet membrane glycoprotein IIb, platelet-specific antigen BAK

Gene Symbol

ITGA2B

Additional CD41/CD61 Products

Product Documents for CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for CD41/CD61 Antibody (BAG 75E5) - Chimeric - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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