CD84/SLAMF5 Antibody (DMC286) - Chimeric

Novus Biologicals | Catalog # NBP3-48311

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # DMC286
View all CD84/SLAMF5 Primary Antibodies »

Product Specifications

Immunogen

CD84/SLAMF5 recombinant protein expressed in mammalian cells (Accession# Q9UIB8). The exact amino acid sequence is proprietary.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).

Scientific Data Images for CD84/SLAMF5 Antibody (DMC286) - Chimeric

CD84/SLAMF5 Antibody (DMC286) - Chimeric

Flow Cytometry: CD84/SLAMF5 Antibody (DMC286) - Chimeric [NBP3-48311]

Flow cytometry analysis of antigen binding of anti-human SLAMF5 mAb(NBP3-48311). (A) NBP3-48311 does not bind to CHO-S cells that do not express SLAMF5. (B) A clear peak shift of NBP3-48311 was seen compared to the control when incubated with SLAMF5-expressing Raji cells, indicating strong binding of NBP3-48311 to SLAMF5. Antibodies were incubated at 5 ug/mL.
CD84/SLAMF5 Antibody (DMC286) - Chimeric

Flow Cytometry: CD84/SLAMF5 Antibody (DMC286) - Chimeric [NBP3-48311]

Flow cytometry analysis with Anti-CD84/CD84/SLAMF5 (DMC286) on HEK293 cells transfected with human CD84/CD84/SLAMF5 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).

Applications for CD84/SLAMF5 Antibody (DMC286) - Chimeric

Application
Recommended Usage

Flow Cytometry

1:100

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified from cell culture supernatant

Reconstitution

Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Formulation

PBS, pH 7.4, 5-8% Trehalose

Preservative

Trehalose

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CD84/SLAMF5

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. CD84 is expressed on mature B cells and B cell lines but not on plasma cell lines. Immunohistochemical studies demonstrate that it strongly stains tissue macrophages. It is also expressed on platelets and at low levels on blood T cells. Cellular expression does not significantly increase after activation.

Long Name

SLAM Family Member 5

Alternate Names

CD84, Ly-9B, SLAMF5

Gene Symbol

CD84

Additional CD84/SLAMF5 Products

Product Documents for CD84/SLAMF5 Antibody (DMC286) - Chimeric

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD84/SLAMF5 Antibody (DMC286) - Chimeric

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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