CDDO-Me

Tocris Bioscience | Catalog # 6646

Nrf2 pathway activator; also NF-κB pathway inhibitor; inhibits IKKβ
Tocris Bioscience
Discontinued Product
6646 has been discontinued. View all Nrf2 Activators products.

Key Product Details

Description

Nrf2 pathway activator; also NF-κB pathway inhibitor; inhibits IKKβ
View all Nrf2 Activators »

Product Description

CDDO-Me is a Nrf2 pathway activator. Induces expression of Nrf-2 regulated, cytoprotective genes in vivo. Also blocks the NF-κB pathway by direct inhibition of IKKβ. Inhibits production of a wide range of inflammatory mediators in vitro.

Product Specifications for CDDO-Me

Molecular Weight

505.69

Formula

C32H43NO4

Storage

Store at -20°C

Chemical Name

2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester

CAS Number

218600-53-4

PubChem ID

400769

InChI Key

WPTTVJLTNAWYAO-KPOXMGGZSA-N

SMILES

[H][C@@]12CC(C)(CC[C@]1(C(OC)=O)CC[C@@]3([C@@]2(C(C=C4[C@]3(CC[C@]5(C(C)(C(C(C#N)=C[C@]45C)=O)C)[H])C)=O)[H])C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25.28 50

Preparing Stock Solutions for CDDO-Me

The following data is based on the product molecular weight 505.69.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.95 mL 19.77 mL 39.55 mL
2.5 mM 0.79 mL 3.95 mL 7.91 mL
5 mM 0.40 mL 1.98 mL 3.95 mL
25 mM 0.08 mL 0.40 mL 0.79 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CDDO-Me

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CDDO-Me

For research use only

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