CDN 1163

  ( 1 citations )    
Product Datasheet
Catalog Number:5869
Chemical Name:4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
Product Details
Citations (1)
Reviews
Biological Activity
SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice.
Technical Data
  • M.Wt:
    320.38
  • Formula:
    C20H20N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    892711-75-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for CDN 1163 include:

1 Citations: Showing 1 - 1

  1. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides.
    Authors: Ferdek Et al.
    Cell.Death.Dis.  2017;8

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