Home / Cyclooxygenase Inhibitors / Celecoxib

Celecoxib

Catalog #: 3786
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3786/10
3786/50
Celecoxib | CAS No. 169590-42-5 | Cyclooxygenase Inhibitors
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Description: Selective cyclooxygenase-2 (COX-2) inhibitor
Alternative Names: SC 58635, Celebrex

Chemical Name: 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide

Purity: ≥99%

Product Details
Citations (2)
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Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). Celecoxib is an anti-inflammatory with shorter plasma half-life in vivo than SC 58121. Displays chemopreventive activity in in vivo tumor models.

Technical Data

M.Wt:
381.37
Formula:
C17H14F3N3O2S
Solubility:
Soluble to 25 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
169590-42-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Celecoxib

The citations listed below are publications that use Tocris products. Selected citations for Celecoxib include:

2 Citations: Showing 1 - 2

  1. CXB Is Associated With Dystrophic Calcification and Aortic Valve Stenosis.
    Authors: Bowler Et al.
    JACC Basic Transl Sci  2019;4:135
  2. The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.
    Authors: Oguh-Olayinka Et al.
    Pathol Oncol Res  2019;

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