Cetirizine dihydrochloride

  ( 3 citations )    
Product Datasheet
Catalog Number:2577
Alternate Names:P 071
Chemical Name:[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity
Histamine H1 receptor antagonist that displays selectivity over other receptors at concentrations up to 10 μM. A non-sedating antihistamine that inhibits histamine release and eosinophil chemotaxis during secondary phase allergic response. Inhibits activation of eosinophils, neutrophils and monocytes in vivo.
Technical Data
  • M.Wt:
    461.81
  • Formula:
    C21H25ClN2O3.2HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    83881-52-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cetirizine dihydrochloride include:

3 Citations: Showing 1 - 3
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  1. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis.
    Authors: Ito Et al.
    PLoS One  2015;11:547
  2. DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair.
    Authors: Kemp Et al.
    J Biol Chem  2014;289:26574
  3. Effects of histamine on cultured interstitial cells of cajal in murine small intestine.
    Authors: Kim Et al.
    Korean J Physiol Pharmacol  2013;17:149

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