Cevimeline hydrochloride

Catalog # Availability Size / Price Qty
3689/10
3689/50
Cevimeline hydrochloride | CAS No. 107220-28-0 | mAChR M1 Agonists
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Description: Selective M1 agonist
Alternative Names: AF 102B, SNI 2011

Chemical Name: cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride

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Biological Activity

Selective M1 receptor agonist. Induces atropine-sensitive contractions of isolated guinea pig ilea and trachea preparations (EC50 values are 3.5 and 3 μM respectively). Reverses AF64A-induced cognitive impairments in vivo.

Technical Data

M.Wt:
235.77
Formula:
C10H17NOS.HCl
Solubility:
Soluble to 75 mM in water and to 50 mM in DMSO
Storage:
Store at -20°C
CAS No:
107220-28-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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