CGP 46381

  ( 4 citations )    
Product Datasheet
Catalog Number:1247
Chemical Name:(3-Aminopropyl)(cyclohexylmethyl)phosphinic acid
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
Brain penetrant, selective GABAB receptor antagonist (IC50 = 4.9 μM).
Technical Data
  • M.Wt:
    219.26
  • Formula:
    C10H22NO2P
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    123691-14-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Novartis Pharma AG
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CGP 46381 include:

4 Citations: Showing 1 - 4
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  1. GABAB receptor antagonist CGP46381 inhibits form-deprivation myopia development in guinea pigs.
    Authors: Cheng Et al.
    Front Cell Neurosci  2015;2015:207312
  2. Intrinsic modulators of auditory thalamocortical transmission.
    Authors: Lee and Sherman
    Hear Res  2012;287:43
  3. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome.
    Authors: Pacey Et al.
    Biomed Res Int  2011;338:897
  4. Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition.
    Authors: Costa Et al.
    J Neurosci  2008;28:8040

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