CGP 60474

Catalog # Availability Size / Price Qty
5471/50
5471/10
Cat.No. 5471 - CGP 60474 | C18H18ClN5O | CAS No. 164658-13-3
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Description: Potent dual cdk1/cdk2 inhibitor

Chemical Name: 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respectively). Also displays low micromolar activity at PKCα. Displays reversible G1/S cell cycle arrest in U2-OS cells.

Technical Data

M.Wt:
355.82
Formula:
C18H18ClN5O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
164658-13-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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