CGS 35066

( 1 Review )    
Product Datasheet
Catalog Number:2512
Chemical Name:α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid
Product Details
Reviews
Biological Activity
Potent endothelin-converting enzyme (ECE) inhibitor that displays > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 values are 22 and 2300 nM respectively). Blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH).
Technical Data
  • M.Wt:
    349.28
  • Formula:
    C16H16NO6P
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    261619-50-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Average Rating: 5 (Based on 1 review)

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  Excellent
  Other Vaishali Soni 01/18/2018
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Summary

Species Other

Other Experimental Details

Other Experimental Details Compound was dissolved in DMSO to make stock and then formulated using 20% captisol in normal saline. However, we can not disclose the dose used to perform study due to confidentiality of data that not yet published.

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